Transform Your Future: Ace the 2026 Certified Diabetes Educator Exam!

Biguanides, particularly Metformin, primarily work to improve insulin sensitivity and reduce hepatic glucose production in individuals with type 2 diabetes. One of their additional benefits is their positive effect on lipid profiles, particularly cholesterol levels. Research has shown that Metformin can lead to a modest reduction in total cholesterol, LDL cholesterol (often referred to as "bad" cholesterol), and triglycerides. This effect contributes to better cardiovascular health, an important consideration for individuals with diabetes who are at increased risk for heart disease.

The ability of Biguanides to lower cholesterol levels can improve overall lipid profiles, which is a significant benefit for patients managing diabetes. This effect accounts for why the correct answer is that Biguanides lower cholesterol levels. In contrast, options that speak about raising cholesterol levels, having no effect, or increasing triglyceride levels do not reflect the established findings regarding the lipid-altering capabilities of Biguanides such as Metformin.